{"id":1919,"date":"2025-09-11T08:10:19","date_gmt":"2025-09-11T08:10:19","guid":{"rendered":"https:\/\/blog.antoniolamarca.it\/?p=1919"},"modified":"2025-09-11T08:13:11","modified_gmt":"2025-09-11T08:13:11","slug":"why-treat-ladenomyosis-with-thermoablation","status":"publish","type":"post","link":"https:\/\/blog.antoniolamarca.it\/en\/why-treat-ladenomyosis-with-thermoablation\/","title":{"rendered":"Why treat adenomyosis with thermoablation"},"content":{"rendered":"Reading Time: <\/span> 2<\/span> minutes<\/span><\/span>

Introduction
\n<\/strong>Adenomyosis is a common gynecological disorder defined by the presence of endometrial glands and stroma within the myometrium. It is associated with uterine enlargement, severe dysmenorrhea, menorrhagia, chronic pelvic pain, and infertility. Traditionally, hysterectomy has been considered the definitive treatment for symptomatic adenomyosis, but this option is not acceptable for women wishing to preserve fertility. Hormonal therapies can provide temporary relief but are often limited by side effects and recurrence of symptoms. Thermoablation has recently emerged as a minimally invasive alternative with encouraging clinical outcomes.<\/p>\n

Advantages of thermoablation<\/strong>
\nThermoablation, delivered via radiofrequency, microwave, or focused ultrasound, produces localized coagulative necrosis within adenomyotic lesions. The procedure is minimally invasive, can be performed in an outpatient setting, and allows rapid recovery. Compared to pharmacologic therapies, thermoablation provides longer-lasting symptom control with fewer systemic adverse effects. Its safety profile is favorable, with low complication rates and reduced perioperative morbidity<\/p>\n

Uterus preservation and fertility<\/strong>
\nUterine-sparing treatment is particularly important in women of reproductive age. Several clinical studies have reported successful pregnancies and deliveries following thermal ablation for adenomyosis. While the data remain limited, these findings suggest that thermoablation not only controls symptoms but also maintains reproductive potential, positioning it as an important alternative to hysterectomy in women with childbearing aspirations.<\/p>\n

Clinical efficacy and novel insights<\/strong>
\nThermoablation is a promising minimally invasive treatment for adenomyosis, offering durable symptom relief, preservation of fertility, and rapid recovery. The possibility of immediate volume reduction and combined therapeutic strategies enhances its clinical value. Future randomized studies are needed to establish long-term reproductive outcomes and refine patient selection criteria.<\/p>\n

Conclusions<\/strong>
\nThermoablation represents one of the most promising treatment options for adenomyosis, capable of reducing symptoms, improving quality of life and preserving fertility. The possibility of an immediate effect on volumetric reduction and an integrated multimodal approach further broadens treatment prospects. Larger randomised trials will be needed to consolidate these results and better define the effects on long-term reproductive outcomes.<\/p>\n

 <\/p>\n

REFERENCES<\/p>\n

Piriyev E, Dieter A, Schiermeier S, Renner S, R\u00f6mer T. Could Transcervical Radiofrequency Ablation Become a Therapy Option for Focal Adenomyosis? In Vivo. 2025 Mar-Apr;39(2):961-968. doi: 10.21873\/invivo.13901. PMID: 40010987; PMCID: PMC11884444.<\/p>\n

Athanasiou A, Fruscalzo A, Dedes I, Mueller MD, Londero AP, Marti C, Guani B, Feki A. Advances in Adenomyosis Treatment: High-Intensity Focused Ultrasound, Percutaneous Microwave Therapy, and Radiofrequency Ablation. J Clin Med. 2024 Sep 29;13(19):5828. doi: 10.3390\/jcm13195828. PMID: 39407887; PMCID: PMC11476787.<\/p>\n

Zhang Q, Liang X, Chen Z. An Updated Review of Thermal Ablation Technology for Uterine Fibroids and Adenomyosis: Focusing on Protecting Fertility. Int J Womens Health. 2024 Sep 23;16:1551-1563. doi: 10.2147\/IJWH.S473005. PMID: 39346931; PMCID: PMC11430362.<\/p>\n

Zhang G, Li L, Sun M, Yu X. Progress in High Intensity Focused Ultrasound Ablation for Fertility Preservation Therapy of Uterine Fibroids and Adenomyosis. Reprod Sci. 2025 Jan;32(1):15-25. doi: 10.1007\/s43032-024-01745-y. Epub 2024 Nov 12. PMID: 39532767; PMCID: PMC11729086.<\/p>","protected":false},"excerpt":{"rendered":"

Reading Time: <\/span> 2<\/span> minutes<\/span><\/span> Introduzione L\u2019adenomiosi \u00e8 una patologia ginecologica caratterizzata dalla presenza di tessuto endometriale all\u2019interno del miometrio, che determina ispessimento uterino, dismenorrea severa, menorragia e, in molti casi, infertilit\u00e0. Colpisce prevalentemente donne in et\u00e0 riproduttiva ed \u00e8 spesso associata a riduzione della qualit\u00e0 della vita e a problematiche riproduttive. Le terapie tradizionali comprendono farmaci ormonali e, nei …<\/p>","protected":false},"author":2,"featured_media":1921,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1919","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts\/1919","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/comments?post=1919"}],"version-history":[{"count":4,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts\/1919\/revisions"}],"predecessor-version":[{"id":1924,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts\/1919\/revisions\/1924"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/media\/1921"}],"wp:attachment":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/media?parent=1919"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/categories?post=1919"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/tags?post=1919"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}