{"id":1794,"date":"2024-03-11T21:21:43","date_gmt":"2024-03-11T21:21:43","guid":{"rendered":"https:\/\/blog.antoniolamarca.it\/?p=1794"},"modified":"2024-03-12T08:34:50","modified_gmt":"2024-03-12T08:34:50","slug":"sperm-quality-decreases-with-lethality-2-2-2","status":"publish","type":"post","link":"https:\/\/blog.antoniolamarca.it\/en\/sperm-quality-decreases-with-lethality-2-2-2\/","title":{"rendered":"EMBOLISATION OF UTERINE FIBROIDS"},"content":{"rendered":"<span class=\"rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading Time: <\/span> <span class=\"rt-time\">3<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span><div class=\"document-page\" data-page=\"1\">\n<div class=\"pdf-page\">\n<div class=\"text-wrapper user-select-text\">\n<div data-canvas-width=\"641.9453333333333\">Uterine artery embolisation for the treatment of symptomatic uterine fibroids is a<\/div>\n<div data-canvas-width=\"641.7986666666662\">minimally invasive procedure first described in 1994, then performed increasingly<\/div>\n<div data-canvas-width=\"642.0186666666664\">often in many Western countries. The method is characterised by a high success rate<\/div>\n<div data-canvas-width=\"642.0039999999995\">85%, capable of providing significant relief in women and characterised by<\/div>\n<div data-canvas-width=\"641.6079999999994\">a low complication rate. Uterine fibroids, the most common type of benign tumour among women in<\/div>\n<div data-canvas-width=\"642.0186666666661\">reproductive age, are associated with heavy menstrual bleeding, abdominal discomfort,<\/div>\n<div data-canvas-width=\"641.3586666666665\">subfertility and a reduced quality of life. Not all women are willing to undergo<\/div>\n<div data-canvas-width=\"641.8426666666666\">uterine removal surgery, current guidelines on the clinical management of ACOG<\/div>\n<div data-canvas-width=\"641.461333333333\">support the technique of uterine embolisation, which is therefore an answer for<\/div>\n<div data-canvas-width=\"641.7986666666662\">those women who wish to preserve their uterus or who have not benefited from the<\/div>\n<div data-canvas-width=\"96.16933333333333\">medical care.<\/div>\n<div data-canvas-width=\"642.1213333333326\">As with any procedure, careful patient selection is crucial. Ideal candidates<\/div>\n<div data-canvas-width=\"641.7253333333331\">for uterine artery embolisation include patients with symptomatic fibroids who wish to<\/div>\n<div data-canvas-width=\"641.52\">preserve the uterus and\/or avoid surgery. Symptoms of uterine fibroids may include<\/div>\n<div data-canvas-width=\"641.3439999999999\">menorrhagia and\/or metrorrhagia; pelvic mass symptoms manifesting as pelvic pain,<\/div>\n<div data-canvas-width=\"641.989333333333\">sense of weight or bloating, dyspareunia, severe cramps or urinary disorders. Absolute contraindications<\/div>\n<div data-canvas-width=\"641.9893333333334\">include pregnancy, untreated active endometritis and suspected malignancy, unless<\/div>\n<div data-canvas-width=\"641.9600000000002\">are not treated for palliative purposes or in addition to surgery, fibroma of less than 1 cm or fibroma<\/div>\n<div data-canvas-width=\"641.9013333333332\">with pedunculated morphology, fibroma localised in the cervix. Allergy to contrast medium, the<\/div>\n<div data-canvas-width=\"642.1213333333332\">coagulopathy, desire for future fertility and renal insufficiency are relative contraindications.<\/div>\n<div data-canvas-width=\"641.7840000000001\">Appropriate counselling should be carried out for the potential risks associated with the technique,<\/div>\n<div data-canvas-width=\"641.7253333333334\">including bleeding, infection, renal damage due to contrast administration<\/div>\n<div data-canvas-width=\"553.9746666666663\">intravascular, impact on fertility and possibility of requiring surgery.<\/div>\n<div data-canvas-width=\"642.1506666666671\">The technique consists of injecting small particles, such as tris-acrylic gelatin spheres (TAG),<\/div>\n<div data-canvas-width=\"641.9306666666664\">non-spherical polyvinyl alcohol (PVA) and spherical PVA, in uterine arteries after selective catheterisation,<\/div>\n<div data-canvas-width=\"641.6813333333333\">entry into the arterial system is usually achieved by unilateral or bilateral access<\/div>\n<div data-canvas-width=\"641.4906666666661\">to the common femoral artery. For the procedure, anaesthesia in<\/div>\n<div data-canvas-width=\"75.01999999999998\">sedation.<\/div>\n<div data-canvas-width=\"641.828\">The expected results after uterine artery embolisation are excellent, the SIR guidelines indicate<\/div>\n<div data-canvas-width=\"641.1826666666666\">that approximately 90% of women should experience a reduction in general symptoms and that more<\/div>\n<div data-canvas-width=\"642.2093333333328\">of 90% should expect the elimination of abnormal uterine bleeding, a reduction of<\/div>\n<div data-canvas-width=\"641.4906666666666\">50-60% of fibroid size and a 40-50% reduction in uterine size. For the<\/div>\n<div data-canvas-width=\"641.7986666666662\">women with ideal procedure selection characteristics, it is possible to achieve a high rate<\/div>\n<div data-canvas-width=\"641.4613333333327\">of symptom control, a satisfaction rate and an increase in the quality of life rate of up to<\/div>\n<div data-canvas-width=\"641.5346666666665\">to 10 years after the procedure. Causes of failure include poor patient selection,<\/div>\n<div data-canvas-width=\"641.4906666666667\">large fibroids, inability to catheterise uterine arteries or embolisation<\/div>\n<div data-canvas-width=\"641.6226666666666\">incomplete artery, arterial spasm leading to poor flow of the embolic artery,<\/div>\n<div data-canvas-width=\"497.44933333333336\">anatomical variants of the uterus or the recanalisation of embolised arteries.<\/div>\n<div data-canvas-width=\"642.0186666666666\">Healthy pregnancies have been reported sporadically following embolisation of the artery<\/div>\n<div data-canvas-width=\"641.4173333333329\">uterine, but the actual fertility rate after the procedure remains uncertain. In contrast, the low<\/div>\n<div data-canvas-width=\"642.2533333333332\">at birth, miscarriage and prematurity have been associated with the technique. Despite the risks<\/div>\n<div data-canvas-width=\"641.2999999999998\">inherent of possible fertility problems, the procedure remains an option for women with fibroids<\/div>\n<div data-canvas-width=\"641.8426666666662\">clinically symptomatic people who wish to become pregnant. However, further<\/div>\n<div data-canvas-width=\"425.9493333333336\">research on conception rates and obstetrical risks of infertility.<\/div>\n<div>\u200b<\/div>\n<div><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1802\" src=\"https:\/\/blog.antoniolamarca.it\/wp-content\/uploads\/2024\/03\/image-1-300x289.png\" alt=\"\" width=\"300\" height=\"289\" srcset=\"https:\/\/blog.antoniolamarca.it\/wp-content\/uploads\/2024\/03\/image-1-300x289.png 300w, https:\/\/blog.antoniolamarca.it\/wp-content\/uploads\/2024\/03\/image-1.png 581w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"document-page\" data-page=\"2\">\n<div class=\"pdf-page\">\n<div class=\"text-wrapper user-select-text\">\n<div data-canvas-width=\"80.832\">References<\/div>\n<div data-canvas-width=\"640.8640000000005\">Jonathan J Keung, Uterine artery embolization: A review of current concepts. Best Pract Res Clin<\/div>\n<div data-canvas-width=\"587.1740000000013\">Obstet Gynaecol. 2018 Jan:46:66-73. doi: 10.1016\/j.bpobgyn.2017.09.003. Epub 2017 Sep 29.<\/div>\n<div data-canvas-width=\"641.732000000001\">Michael Young, et al. Uterine Fibroid Embolization. Treasure Island (FL): StatPearls Publishing; 2024<\/div>\n<div data-canvas-width=\"98.71400000000001\">Jan 2023 Jul 3.<\/div>\n<div data-canvas-width=\"641.3120000000016\">Parker E Ludwig, et al. Pregnancy success and outcomes after uterine fibroid embolisation: updated<\/div>\n<div data-canvas-width=\"192.17800000000005\">review of published literature.<\/div>\n<div data-canvas-width=\"448.78400000000056\">Br J Radiol. 2020 Jan;93(1105):20190551. doi: 10.1259\/bjr.20190551.<\/div>\n<div data-canvas-width=\"108.83600000000004\">Epub 2019 Oct 8.<\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><span class=\"rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading Time: <\/span> <span class=\"rt-time\">3<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span> L\u2019embolizzazione dell\u2019arteria uterina per il trattamento dei fibromi uterini sintomatici \u00e8 una procedura minimamente invasiva descritta per la prima volta nel 1994, eseguita poi sempre pi\u00f9 spesso in molti paesi occidentali. Il metodo \u00e8 caratterizzato da un&#8217;elevata percentuale di successo tecnico pari a circa l&#8217;85%, in grado di dare un sollievo significativo nelle donne e  &#8230;<\/p>","protected":false},"author":1,"featured_media":1801,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-classic-ns.php","format":"standard","meta":{"om_disable_all_campaigns":false,"footnotes":""},"categories":[5,2],"tags":[],"class_list":["post-1794","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-featured","category-press"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts\/1794","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/comments?post=1794"}],"version-history":[{"count":2,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts\/1794\/revisions"}],"predecessor-version":[{"id":1803,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/posts\/1794\/revisions\/1803"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/media\/1801"}],"wp:attachment":[{"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/media?parent=1794"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/categories?post=1794"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.antoniolamarca.it\/en\/wp-json\/wp\/v2\/tags?post=1794"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}